The MATRIS device, class IIb medical device, is a system of plates and cancellous screws which are intended to be implanted and assembled on the spine via anterior approach in order to help achieve vertebral fusion between two or more vertebras. Spinal fusion aims to reduce significantly and sustainably patient’s pain and disability. This surgery, performed by orthopedic surgeons or neurosurgeons on skeletally mature patients, is conducted in the cervical region of the spine. Specific implants have been designed, developed and distributed by Novaspine for this treated area. Medical indications, contraindications, general adverse events, lifetime and safety measures are gathered in the IFU provided with the MATRIS system. Performance claims focuses on fusion rate, pain reduction and disability reduction, while safety claims concern plate or screw breakage, screw loosening and dysphagia rates. All the MATRIS products have been CE marked and implanted since 2006.